CNR résistance aux antibiotiques
analyse_sequence antibiogramme Test

Bienvenue sur le site du CNR de la Résistance aux Antibiotiques

Depuis le 01 janvier 2012, le CNR est coordonné par le Laboratoire de Bactériologie du Pr Plésiat (CHRU de Besançon).

Centre National de Référence
de la Résistance aux Antibiotiques

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Les Laboratoires

Accueil > Les Laboratoires > CHU de Rennes > Publications de l’équipe

Les Laboratoires

Publications de l’équipe



Isnard C, Malbruny B, Leclercq R, Cattoir V. Genetic basis for in vitro and in vivo resistance to lincosamides, streptogramins A, and pleuromutilins (LSAP phenotype) in Enterococcus faecium. Antimicrob Agents Chemother. 2013 Sep;57(9):4463-9.

Gravey F, Galopin S, Grall N, Auzou M, Andremont A, Leclercq R, Cattoir V. Lincosamide resistance mediated by lnu(C) (L phenotype) in a Streptococcus anginosus clinical isolate. J Antimicrob Chemother. 2013 Nov;68(11):2464-7.

Leclercq R, Oberlé K, Galopin S, Cattoir V, Budzinski H, Petit F. Changes in enterococcal populations and related antibiotic resistance along a medical center-wastewater treatment plant-river continuum. Appl Environ Microbiol. 2013 79(7):2428-34.

Cattoir V, Leclercq R. Twenty-five years of shared life with vancomycin-resistant enterococci: is it time to divorce? J Antimicrob Chemother. 2012 68(4):731-42.

Lebreton F, van Schaik W, Sanguinetti M, Posteraro B, Torelli R, Le Bras F, Verneuil N, Zhang X, Giard JC, Dhalluin A, Willems RJ, Leclercq R, Cattoir V. AsrR is an oxidative stress sensing regulator modulating Enterococcus faecium opportunistic traits, antimicrobial resistance, and pathogenicity. PLoS Pathog. 2012;8(8):e1002834.

Lebreton F, Le Bras F, Reffuveille F, Ladjouzi R, Giard JC, Leclercq R, Cattoir V. Galleria mellonella as a model for studying Enterococcus faecium host persistence. J Mol Microbiol Biotechnol. 2011;21(3-4):191-6.

Lebreton F, Depardieu F, Bourdon N, Fines-Guyon M, Berger P, Camiade S, Leclercq R, Courvalin P, Cattoir V. D-Ala-d-Ser VanN-type transferable vancomycin resistance in Enterococcus faecium. Antimicrob Agents Chemother. 2011 Oct;55(10):4606-12. doi: 10.1128/AAC.00714-11.

Bérenger R, Bourdon N, Auzou M, Leclercq R, Cattoir V. In vitro activity of new antimicrobial agents against glycopeptide-resistant Enterococcus faecium clinical isolates from France between 2006 and 2008. Med Mal Infect. 2011 Aug;41(8):405-9. doi: 10.1016/j.medmal.2010.12.013.

Bourdon N, Fines-Guyon M, Thiolet JM, Maugat S, Coignard B, Leclercq R, Cattoir V. Changing trends in vancomycin-resistant enterococci in French hospitals, 2001-08. J Antimicrob Chemother. 2011 Apr;66(4):713-21.

Malbruny B, Werno AM, Murdoch DR, Leclercq R, Cattoir V. Cross-resistance to lincosamides, streptogramins A, and pleuromutilins due to the lsa(C) gene in Streptococcus agalactiae UCN70. Antimicrob Agents Chemother. 2011 Apr;55(4):1470-4. Erratum in: Antimicrob Agents Chemother. 2011 Jun;55(6):3065.

Lascols C, Legrand P, Mérens A, Leclercq R, Muller-Serieys C, Drugeon HB, Kitzis MD, Reverdy ME, Roussel-Delvallez M, Moubareck C, Brémont S, Miara A, Gjoklaj M, Soussy CJ. In vitro antibacterial activity of ceftobiprole against clinical isolates from French teaching hospitals: proposition of zone diameter breakpoints. Int J Antimicrob Agents. 2011 Mar;37(3):235-9.

Fortineau N, Bourdon N, Leclercq R, Vachée A, Delarbre JM, Maugat S, Robert J; ONERBA. Low carriage of vancomycin-resistant enterococci in the digestive tract of French hospitalised patients: a nationwide prospective study in 2006. J Hosp Infect. 2011 Feb;77(2):179-81.

Lascols C, Legrand P, Mérens A, Leclercq R, Armand-Lefevre L, Drugeon HB, Kitzis MD, Muller-Serieys C, Reverdy ME, Roussel-Delvallez M, Moubareck C, Lemire A, Miara A, Gjoklaj M, Soussy CJ. In vitro antibacterial activity of doripenem against clinical isolates from French teaching hospitals: proposition of zone diameter breakpoints. Eur J Clin Microbiol Infect Dis. 2011 Apr;30(4):475-82.

Cattoir V, Leclercq R. [Enterococci resistant to glycopeptides]. Med Sci (Paris). 2010 Nov;26(11):936-42.

Bourdon N, Lemire A, Fines-Guyon M, Auzou M, Périchon B, Courvalin P, Cattoir V, Leclercq R. Comparison of four methods, including semi-automated rep-PCR, for the typing of vancomycin-resistant Enterococcus faecium. J Microbiol Methods. 2011 Jan;84(1):74-80.

Bourdon N, Bérenger R, Lepoultier R, Mouet A, Lesteven C, Borgey F, Fines-Guyon M, Leclercq R, Cattoir V. Rapid detection of vancomycin-resistant enterococci from rectal swabs by the Cepheid Xpert vanA/vanB assay. Diagn Microbiol Infect Dis. 2010 Jul;67(3):291-3.

Cattoir V, Daurel C. [Update on antimicrobial chemotherapy]. Med Mal Infect.  2010 Mar;40(3):135-54.

Cattoir V, Huynh TM, Bourdon N, Auzou M, Leclercq R. Trimethoprim resistance  genes in vancomycin-resistant Enterococcus faecium clinical isolates from France. Int J Antimicrob Agents. 2009 Oct;34(4):390-2.

Boumghar-Bourtchaï L, Dhalluin A, Malbruny B, Galopin S, Leclercq R. Influence of recombination on development of mutational resistance to linezolid in Enterococcus faecalis JH2-2. Antimicrob Agents Chemother. 2009 Sep;53(9):4007-9.

Leclercq R. Epidemiological and resistance issues in multidrug-resistant staphylococci and enterococci. Clin Microbiol Infect. 2009 Mar;15(3):224-31.

Rio Y, Okamba P, Staal A, Didion J, Jurin F; groupe d'étude TEST. [Activity of tigecycline against pathogen bacteria isolated in respiratory infectious disease in Europe. TEST study 2004-2007]. Pathol Biol (Paris). 2009 Feb;57(1):13-6.

Werner G, Coque TM, Hammerum AM, Hope R, Hryniewicz W, Johnson A, Klare I, Kristinsson KG, Leclercq R, Lester CH, Lillie M, Novais C, Olsson-Liljequist B, Peixe LV, Sadowy E, Simonsen GS, Top J, Vuopio-Varkila J, Willems RJ, Witte W, Woodford N. Emergence and spread of vancomycin resistance among enterococci in Europe. Euro Surveill. 2008 Nov 20;13(47).

Kempf I, Hellard G, Perrin-Guyomard A, Gicquel-Bruneau M, Sanders P, Leclercq R. Prevalence of high-level vancomycin-resistant enterococci in French broilers and pigs. Int J Antimicrob Agents. 2008 Nov;32(5):463-4.

Fortineau N, Leclercq R, Maugat S, Robert J; Conseil Scientifique de l'ONERBA. [Vancomycin-resistant enterococci: ONERBA networks data and results of the national 2006 survey on digestive carriage]. Med Mal Infect. 2008 Jun;38 Suppl 2:S65-7.

Achard A, Guérin-Faublée V, Pichereau V, Villers C, Leclercq R. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. Antimicrob Agents Chemother. 2008 Aug;52(8):2767-70.

Rodloff AC, Leclercq R, Debbia EA, Cantón R, Oppenheim BA, Dowzicky MJ. Comparative analysis of antimicrobial susceptibility among organisms from France, Germany, Italy, Spain and the UK as part of the tigecycline evaluation and surveillance trial. Clin Microbiol Infect. 2008 Apr;14(4):307-14.

Arsène S, Leclercq R. Role of a qnr-like gene in the intrinsic resistance of Enterococcus faecalis to fluoroquinolones. Antimicrob Agents Chemother. 2007 Sep;51(9):3254-8.

Moreillon P, Wilson WR, Leclercq R, Entenza JM. Single-dose oral amoxicillin or linezolid for prophylaxis of experimental endocarditis due to vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis. Antimicrob Agents Chemother. 2007 May;51(5):1661-5.

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